Amy Crystal is one of two unplayable AMS agents in House of the Dead 2. Along with Harry Harris, she joins and aids James Taylor and Gary Stewart during their mission in Venice, Italy. She is first mentioned by G at the beginning of the game's first chapter, she then appears with Harry after James and Gary defeat Judgment. She appears again along Harry near Sunset Bridge or on a motor boat with Harry (depending which path the player takes) before and after James and Gary face Hierophant. She drives the motor boat throughout the game's third chapter before going with Harry to the Coliseum after recieving a phone call where she is informed that Goldman has left a message for the AMS agents there, leaving James and Gary to face Tower. After James and Gary defeat Tower they receive a call from an alarmed Amy that is cut short because of a giant monster attacking her and Harry. The creature is eventually identified as Strength, the boss of the game's fourth chapter. When James and Gary arrive at the Colluseum they are greeted with a pre-recorded message by Goldman himself before Strength is unleashed again. After James and Gary defeat it they are given the keys to a car by an injured Harry, with Amy staying with him to tend to his injuries. Amy can be seen again in the game's normal ending along with Harry, G, and the citizens of Venice cheering for the James and Gary outside Goldman's headquarters.
- She is seen wielding a silver H&K MK23, however there are no silver H&K MK23 in real life because its made of Carbon Fiber A.K.A. Full Metal.
- Amy Crystal can be used in The House Of The Dead 2's original mode.
- Fans of the series have speculated that because of her behavior throughout the game Amy might have a crush on Gary Stewart, however this is a misconception since in the game's manual states that because of Gary's young age she tends to act as a big sister towards him and has not accepted him as a special agent yet.
- Many fans also believe Empress is Amy Crystal.