(Sega AM1's universe)
The EFI Genome Ward and the DBR Institute are two facilities within the EFI Research Facility, as well as levels in The House of the Dead III. Depending on the player's decisions, they will journey through either facility.
As they disembark the elevator to either facility, Lisa Rogan asks G what happened to the world. The latter explains the 1998 Curien Mansion case, a humanity-threatening project that he and her father stopped.
After battling through the creature-infested facility, the pair get trapped in a cage strewn with hanging corpses. A sloth-like creature named Fool fights Lisa and G; upon defeat, it falls to its death.
Back in another elevator, Lisa wonders if her father and G fully stopped Dr. Curien's plans. G speculates that someone is continuing his legacy.