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The immortality serum was a fluid created by Castillo Sermano to achieve immortality. It appears in the 2003 film House of the Dead.

History[]

Castillo created the serum to live forever, only to discover that it could not prevent his body from deteriorating. Thus, Castillo used the serum to make zombies, murdering visitors of the Isla del Morte and reusing their dead appendages to keep Castillo keep his body in the best shape.

While Castillo was ultimately killed by one survivor, Alicia, Professor Roy Curien used the serum and Castillo's research for his own purpose (as depicted in the second film, House of the Dead 2).

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